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Food and Drug Administration (FDA) in 1987 under the Prinivil brand, and it is still used as a first-line treatment for hypertension and the prevention of cardiac events. In Australia it is marketed by AlphaPharm with the brand name Lisodur® 8600 Rockville Pike, Bethesda, MD, 20894 USA Contact Policies FOIA HHS Vulnerability Disclosure National Library of Medicine National Institutes of Health Department of Health and Human Services USA. [23] Scientists at Merck created lisinopril by systematically altering each structural unit of enalaprilat, substituting various amino acids Interestingly, lisinopril and other ACE inhibitors were developed from the venom of a poisonous Brazilian snake. The generic version can be made by Watson Pharmaceuticals, Sandoz Inc. My rosuvastatin (generic of Crestor) was made by Glenmark Pharmaceuticals which, per Wikipedia, "is a pharmaceutical company headquartered in Mumbai, India that was founded in 1977 by Gracias. Lisinopril is the generic name for a couple of brand names available in the USA such as Prinivil (made by Merck & Co. Lisinopril Side Effects Headache Dizziness or fainting (syncope) Coughing Nausea Rash. In the early 1980s, hypertension conferences were routinely enlivened by the poisonous Brazilian viper, Bothrops jararaca.. Lisinopril is a synthetic peptide derivative of captopril. Is it true that it is made from snake venom? Question posted by 4redeagle on 21 July 2013. In this article on landmark drugs, Jenny Bryan looks at the discovery of captopril and how it changed cardiovascular treatment. Gov Follow PubChem Facebook Twitter Posts PubChem ® is a registered trademark of the National Library of Medicine. Last updated on 30 July 2013 by Anonymous. This medication was first developed by Merck & Co. ) Lisinopril was approved by the U. Lisinopril has some key features that make it different from enalapril and captopril; 1) it has a long half-life, 2) it is hydrophilic, and 3) it is not broken down by the liver. , Mylan, Lupin, Teva Pharmaceuticals, Apotex Corporation, Ranbaxy, and many more Lisinopril is classified as an angiotensin-converting enzyme inhibitor and has been available for nearly three decades. (ACE stands for angiotensin-converting enzyme. Mom was prescribed Lisinopril in December 2009; it made her extremely drained and she lost a lot of weight. , and is marketed worldwide by Merck with the brand name Prinivil® and by AstraZeneca with the brand name Zestril®. From snake venom to ACE inhibitor — the discovery and rise of captopril. Then she started using a four-prong cane to walk anywhere. I would like to know what lisinopril is made out of.